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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW10182
    • 應(yīng)用 : 僅供科研使用
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    • 規(guī)格 ：100ul/200ul/25ul
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中文名稱(chēng):  兔抗JPT1多克隆抗體  

英文名稱(chēng): Anti-JPT1 rabbit polyclonal antibody

別    名: Jupiter microtubule associated homolog 1; HN1; ARM2; HN1A

儲(chǔ)    存: 冷凍（-20℃）

抗    原: JPT1

宿    主: Rabbit

相關(guān)類(lèi)別: 一抗

反應(yīng)種屬: Human, Mouse, Rat

標(biāo) 記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).

Applications:

ELISA, IHC

Name of antibody:

JPT1

Immunogen:

Fusion protein of human JPT1

Full name:

Jupiter microtubule associated homolog 1

Synonyms:

HN1; ARM2; HN1A

SwissProt:

Q9UK76

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human cervical cancer

IHC Recommend dilution:

30-150








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