購(gòu)物車
幫助
021-54845833/15800441009
儲(chǔ) 存： 冷凍（-20℃）
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
KLK7 |
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Immunogen: |
Fusion protein of human KLK7 |
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Full name: |
kallikrein-related peptidase 7 |
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Synonyms： |
hK7, SCCE, PRSS6 |
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SwissProt: |
P49862 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human colon cancer and human ovarian cancer |
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IHC Recommend dilution: |
25-100 |
