購物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
Background:
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
Applications:
ELISA, IHC
Name of antibody:
KRT13
Immunogen:
Fusion protein of human KRT13
Full name:
keratin 13
Synonyms：
K13; CK13
SwissProt:
P13646
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human thyroid cancer and human lung cancer
IHC Recommend dilution:
50-200
