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    • 品牌 : 通蔚生物
    • 目錄號 : TW11058
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 ：100ul/200ul/25ul
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中文名稱： 兔抗KSR2多克隆抗體

英文名稱： Anti-KSR2 rabbit polyclonal antibody

相關(guān)類別： 一抗

儲     存： 冷凍（-20℃） 避光

抗     原： KSR2

宿     主： Rabbit

反應(yīng)種屬： Human Mouse

標(biāo) 記 物： Unconjugate

克隆類型： Unconjugate

技術(shù)規(guī)格

Background:

Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Applications:

WB, IF

Name of antibody:

KSR2

Immunogen:

Synthesized peptide derived from internal of human KSR2.

Full name:

kinase suppressor of ras 2

Synonyms：

0

SwissProt:

Q6VAB6

WB Predicted band size:

108 kDa

WB Positive control:

COS7,293,3T3 cell lysates

WB Recommended dilution:

500-3000

IF positive control:

Hela cells

IF Recommend dilution:

100-500









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