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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW11979
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
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中文名稱: 小鼠抗SEMA4D單克隆抗體

英文名稱: Anti-SEMA4D mouse monoclonal antibody

別    名: semaphorin 4D; CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G

相關(guān)類別: 一抗

儲(chǔ)    存: 冷凍(-20℃)

宿    主: Mouse

抗    原: SEMA4D

反應(yīng)種屬: Human

標(biāo) 記 物: Unconjugate

克隆類型: mouse monoclonal

技術(shù)規(guī)格

Background:

Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Applications:

WB, IHC

Name of antibody:

SEMA4D

Immunogen:

Fusion protein of human SEMA4D

Full name:

semaphorin 4D

Synonyms:

CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G

SwissProt:

Q92854

IHC positive control:

Human kidney tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

96 KD

WB Positive control:

Jurkat cell lysate

WB Recommended dilution:

500-2000