購(gòu)物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
|
Background: |
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]. |
|
Applications: |
WB, IHC, IF |
|
Name of antibody: |
PIK3R5 |
|
Immunogen: |
Fusion protein of human PIK3R5 |
|
Full name: |
phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2 |
|
Synonyms: |
F730038I15Rik; FOAP-2; p101; P101-PI3K |
|
SwissProt: |
Q8WYR1 |
|
IHC positive control: |
adenocarcinoma of human ovary tissue and human pancreas tissue; human tonsil tissue |
|
IHC Recommend dilution: |
30-150 |
|
WB Predicted band size: |
97 kDa |
|
WB Positive control: |
Human Brain tissue lysate |
|
WB Recommended dilution: |
500-2000 |
