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Background: |
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CLN5 |
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Immunogen: |
Synthetic peptide of human CLN5 |
|
Full name: |
ceroid-lipofuscinosis, neuronal 5 |
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Synonyms: |
NCL |
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SwissProt: |
O75503 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
40-200 |
|
WB Predicted band size: |
41 kDa |
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WB Positive control: |
231 cell lysate |
|
WB Recommended dilution: |
200-1000 |

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