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Background: |
The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. |
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Applications: |
WB, IHC |
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Name of antibody: |
CLOCK |
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Immunogen: |
Synthesized peptide derived from Internal of human Clock. |
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Full name: |
clock circadian regulator |
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Synonyms: |
KAT13D; bHLHe8 |
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SwissProt: |
O15516 |
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IHC positive control: |
Human skeletal muscle tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
95 kDa |
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WB Positive control: |
Huvec cells lysate |
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WB Recommended dilution: |
500-3000 |

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