Name: AADAC 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：AADAC 抗原（重組蛋白）

英文名稱： AADAC Antigen (Recombinant Protein)

別名： Arylacetamide deacetylase; DAC; CES5A1

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human AADAC

技術規(guī)格：

Full name:	Arylacetamide deacetylase
Synonyms:	DAC; CES5A1
Swissprot:	P22760
Gene Accession:	BC032309
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.

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