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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW15693
    • 應(yīng)用 : 僅供科研使用
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中文名稱：ABI3BP抗原（重組蛋白）

英文名稱： ABI3BP Antigen (Recombinant Protein)

別      名： TARSH; NESHBP

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概  述：

Fusion protein corresponding to a region derived from 731-930 amino acids of human ABI3BP


技術(shù)規(guī)格：

Full name:

ABI family, member 3 (NESH) binding protein

Synonyms:

TARSH; NESHBP

Swissprot:

Q7Z7G0

Gene Accession:

BC030221

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

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