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  • AMIGO2 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW15902
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:AMIGO2 抗原(重組蛋白)

英文名稱: AMIGO2 Antigen (Recombinant Protein)

別      名: adhesion molecule with Ig-like domain 2; ALI1; DEGA; AMIGO-2

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to a region derived from 420-522 amino acids of human AMIGO2

   
技術(shù)規(guī)格:

Full name:

adhesion molecule with Ig-like domain 2

Synonyms:

ALI1; DEGA; AMIGO-2

Swissprot:

Q86SJ2

Gene Accession:

BC047595

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction