Name: ANKMY2 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)：ANKMY2 抗原（重組蛋白）

英文名稱(chēng)： ANKMY2 Antigen (Recombinant Protein)

別名： ankyrin repeat and MYND domain containing 2; ZMYND20

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述：

Fusion protein corresponding to N terminal 320 amino acids of human ANKMY2

技術(shù)規(guī)格：

Full name:	ankyrin repeat and MYND domain containing 2
Synonyms:	ZMYND20
Swissprot:	Q8IV38
Gene Accession:	BC035353
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.

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