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  • ACTG1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16079
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
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文名稱: ACTG1抗原(重組蛋白)

英文名稱: ACTG1 Antigen (Recombinant Protein)

儲(chǔ)     存: 冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 4-379 amino acids of human ACTG1

技術(shù)規(guī)格

Full name:

actin, gamma 1

Synonyms:

ACT, ACTG, BRWS2, DFNA20, DFNA26

Swissprot:

P63261

Gene Accession:

BC018774

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.