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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16088
    • 應(yīng)用 : 僅限于科研使用
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    • 規(guī)格 ：1mg/100ug
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中文名稱： ACMSD抗原（重組蛋白）

英文名稱： ACMSD Antigen (Recombinant Protein)

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

Aminocarboxymuconate semialdehyde decarboxylase

Swissprot:

Q8TDX5

Gene Accession:

BC016018

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.



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