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中文名稱： CLCN5 抗原（重組蛋白）

英文名稱： CLCN5 Antigen (Recombinant Protein)

別     名： chloride voltage-gated channel 5; XRN; CLC5; XLRH; CLCK2; ClC-5; DENTS; NPHL1; NPHL2; hCIC-K2

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 552-746 amino acids of human CLCN5

技術(shù)規(guī)格

Full name:

chloride voltage-gated channel 5

Synonyms:

XRN; CLC5; XLRH; CLCK2; ClC-5; DENTS; NPHL1; NPHL2; hCIC-K2

Swissprot:

P51795

Gene Accession:

BC130429

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.



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