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Background: |
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CYLD |
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Immunogen: |
Synthetic peptide of human CYLD |
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Full name: |
cylindromatosis (turban tumor syndrome) |
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Synonyms: |
EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2 |
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SwissProt: |
Q9NQC7 |
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IHC positive control: |
Human gastric cancer and human brain |
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IHC Recommend dilution: |
50-200 |
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021-54845833/15800441009
