概 述
| 
					 Full name:  | 
				
					 dermcidin  | 
			
| 
					 Synonyms:  | 
				
					 PIF; AIDD; DSEP; HCAP; DCD-1  | 
			
| 
					 Swissprot:  | 
				
					 P81605  | 
			
| 
					 Gene Accession:  | 
				
					 BC062682  | 
			
| 
					 Purity:  | 
				
					 >85%, as determined by Coomassie blue stained SDS-PAGE  | 
			
| 
					 Expression system:  | 
				
					 Escherichia coli  | 
			
| 
					 Tags:  | 
				
					 His tag C-Terminus, GST tag N-Terminus  | 
			
| 
					 Background:  | 
				
					 This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms.  | 
			
購(gòu)物車
幫助
021-54845833/15800441009
              