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中文名稱: KLK15抗原(重組蛋白)

英文名稱: KLK15 Antigen (Recombinant Protein)

別       名: ACO, HSRNASPH

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 22-256 amino acids of human KLK15

技術(shù)規(guī)格

Full name:

kallikrein-related peptidase 15

Synonyms:

ACO, HSRNASPH

Swissprot:

Q9H2R5

Gene Accession:

BC126137

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.

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