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  • CABLES1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16846
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:  CABLES1抗原(重組蛋白)

英文名稱: CABLES1 Antigen (Recombinant Protein)

別      名: CABL1; IK3-1; CABLES; HsT2563

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to C terminal 250 amino acids of human CABLES1


技術(shù)規(guī)格: 

Full name:

Cdk5 and Abl enzyme substrate 1

Synonyms:

CABL1; IK3-1; CABLES; HsT2563

Swissprot:

Q8TDN4

Gene Accession:

BC037218

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.