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Background: |
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
TSC2 |
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Immunogen: |
Synthetic peptide of humanTSC2 |
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Full name: |
tuberous sclerosis 2 |
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Synonyms: |
LAM; TSC4; PPP1R160 |
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SwissProt: |
P49815 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
10-50 |
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WB Predicted band size: |
201 kDa |
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WB Positive control: |
A172 cells |
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WB Recommended dilution: |
200-1000 |

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