Name: CD27抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： CD27抗原（重組蛋白）

英文名稱： CD27 Antigen (Recombinant Protein)

別名： T14; S152; Tp55; TNFRSF7; S152. LPFS2

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述：

Fusion protein corresponding to a region derived from 20-191 amino acids of human CD27

技術(shù)規(guī)格：

Full name:	CD27 molecule
Synonyms:	T14; S152; Tp55; TNFRSF7; S152. LPFS2
Swissprot:	P26842
Gene Accession:	BC012160
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

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