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中文名稱: NGF抗原(重組蛋白)

英文名稱: NGF Antigen (Recombinant Protein)

別      名: NGFB; HSAN5; Beta-NGF

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 122-241 amino acids of human NGF

技術(shù)規(guī)格

Full name:

nerve growth factor (beta polypeptide)

Synonyms:

NGFB; HSAN5; Beta-NGF

Swissprot:

P01138

Gene Accession:

BC126148

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

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