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  • CXCR4抗原(重組蛋白)

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    • 目錄號(hào) : TW17008
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中文名稱(chēng):  CXCR4抗原(重組蛋白)

英文名稱(chēng): CXCR4 Antigen (Recombinant Protein)

別      名: FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概  述:

Fusion protein corresponding to a region derived from 262-352 amino acids of human CXCR4


技術(shù)規(guī)格: 

Full name:

chemokine (C-X-C motif) receptor 4

Synonyms:

FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E

Swissprot:

P61073

Gene Accession:

BC020968

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.


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