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    • 品牌 : 通蔚生物
    • 目錄號 : TW17041
    • 應(yīng)用 : 僅供科研使用
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中文名稱： PHF6抗原（重組蛋白）

英文名稱： PHF6 Antigen (Recombinant Protein)

別      名： BFLS; BORJ; CENP-31

儲      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 63-312 amino acids of human PHF6

技術(shù)規(guī)格

Full name:

PHD finger protein 6

Synonyms:

BFLS; BORJ; CENP-31

Swissprot:

Q8IWS0

Gene Accession:

BC005994

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

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