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					 Background:  | 
				
					 This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.  | 
			
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					 Applications:  | 
				
					 ELISA, IHC  | 
			
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					 Name of antibody:  | 
				
					 DDAH1  | 
			
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					 Immunogen:  | 
				
					 Synthetic peptide of human DDAH1  | 
			
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					 Full name:  | 
				
					 dimethylarginine dimethylaminohydrolase 1  | 
			
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					 Synonyms:  | 
				
					 DDAH  | 
			
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					 SwissProt:  | 
				
					 O94760  | 
			
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					 ELISA Recommended dilution:  | 
				
					 1000-5000  | 
			
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					 IHC positive control:  | 
				
					 Human thyroid cancer and Human brain  | 
			
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					 IHC Recommend dilution:  | 
				
					 50-200  | 
			
	
	
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