Name: FMR1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： FMR1抗原（重組蛋白）

英文名稱： FMR1 Antigen (Recombinant Protein)

別名： POF; FMRP; POF1; FRAXA

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述：

Fusion protein corresponding to a region derived from 1-294 amino acids of human FMR1

技術(shù)規(guī)格：

Full name:	fragile X mental retardation 1
Synonyms:	POF; FMRP; POF1; FRAXA
Swissprot:	Q06787
Gene Accession:	NP_002015
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

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