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中文名稱:  GLIPR1抗原(重組蛋白)

英文名稱: GLIPR1 Antigen (Recombinant Protein)

別  名: GLIPR; RTVP1; CRISP7

儲  存 冷凍(-20℃)

相關類別: 抗原

概  述:

Fusion protein corresponding to a region derived from 22-230 amino acids of human GLIPR1


技術規(guī)格:

Full name:

GLI pathogenesis-related 1

Synonyms:

GLIPR; RTVP1; CRISP7

Swissprot:

P48060

Gene Accession:

BC012510

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.


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