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    • 目錄號 : TW17631
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中文名稱： NCF2抗原（重組蛋白）

英文名稱： NCF2 Antigen (Recombinant Protein)

別      名： neutrophil cytosolic factor 2; NCF-2; NOXA2; P67PHOX; P67-PHOX
儲      存： 冷凍（-20℃）
相關類別： 抗原

概述

Fusion protein corresponding to a region derived from 240-526 amino acids of human NCF2

技術規(guī)格

Full name:

neutrophil cytosolic factor 2

Synonyms:

NCF-2; NOXA2; P67PHOX; P67-PHOX

Swissprot:

P19878

Gene Accession:

BC001606

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

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