購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱：兔抗TTI1多克隆抗體
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Background: |
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TTI1 |
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Immunogen: |
Synthetic peptide of humanTTI1 |
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Full name: |
TELO2 interacting protein 1 |
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Synonyms： |
smg-10; KIAA0406 |
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SwissProt: |
O43156 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human prostate cancer and Human esophagus cancer |
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IHC Recommend dilution: |
30-150 |
