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    • 品牌 : 通蔚生物
    • 目錄號 : TW17944
    • 應(yīng)用 : 僅供科研使用
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中文名稱：  PAICS抗原（重組蛋白）

英文名稱： PAICS Antigen (Recombinant Protein)

別       名： phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase; ADE2; AIRC; PAIS; ADE2H1
儲       存： 冷凍（-20℃）
相關(guān)類別： 抗原

概述

Fusion protein corresponding to N terminal 260 amino acids of human PAICS

技術(shù)規(guī)格

Full name:

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

Synonyms:

ADE2; AIRC; PAIS; ADE2H1

Swissprot:

P22234

Gene Accession:

BC010273

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

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