Name: PLEKHA1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)：PLEKHA1抗原（重組蛋白）

英文名稱(chēng)： PLEKHA1 Antigen (Recombinant Protein)

別名： pleckstrin homology domain containing A1; TAPP1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Fusion protein corresponding to a region derived from 205-404 amino acids of human PLEKHA1

技術(shù)規(guī)格

Full name:	pleckstrin homology domain containing A1
Synonyms:	TAPP1
Swissprot:	Q9HB21
Gene Accession:	BC001136
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

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