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    • 目錄號 : TW18181
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中文名稱：  KLK6 抗原（重組蛋白）

英文名稱： KLK6 Antigen (Recombinant Protein)

別      名： kallikrein-related peptidase 6; hK6; Bssp; Klk7; SP59; PRSS9; PRSS18

儲      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 22-244 amino acids of human KLK6


技術(shù)規(guī)格

Full name:

kallikrein-related peptidase 6

Synonyms:

hK6; Bssp; Klk7; SP59; PRSS9; PRSS18

Swissprot:

Q92876

Gene Accession:

BC015525

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.


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