Name: ELF3抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ELF3抗原（重組蛋白）

英文名稱： ELF3 Antigen (Recombinant Protein)

別名： ERT; ESX; EPR-1; ESE-1

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 1-200 amino acids of human ELF3

技術(shù)規(guī)格：

Full name:	E74 like ETS transcription factor 3
Synonyms:	ERT; ESX; EPR-1; ESE-1
Swissprot:	P78545
Gene Accession:	BC003569
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

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