Name: FDPS抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：FDPS抗原（重組蛋白）

英文名稱： FDPS Antigen (Recombinant Protein)

別名： FPS; FPPS; POROK9

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 220-419 amino acids of human FDPS

技術(shù)規(guī)格：

Full name:	farnesyl diphosphate synthase
Synonyms:	FPS; FPPS; POROK9
Swissprot:	P14324
Gene Accession:	BC010004
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

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