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Background: |
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DNTT |
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Immunogen: |
Fusion protein of human DNTT |
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Full name: |
DNA nucleotidylexotransferase |
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Synonyms: |
TDT |
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SwissProt: |
P04053 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
20-100 |
購物車
幫助
021-54845833/15800441009
