購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱： 兔抗MMP8多克隆抗體
英文名稱： Anti-MMP8 rabbit polyclonal antibody
別 名： HNC, CLG1, MMP-8, PMNL-CL
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MMP8
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
MMP8 |
|
Immunogen: |
Synthetic peptide of human MMP8 |
|
Full name: |
matrix metallopeptidase 8 (neutrophil collagenase) |
|
Synonyms： |
HNC, CLG1, MMP-8, PMNL-CL |
|
SwissProt: |
P22894 |
|
ELISA Recommended dilution: |
2000-5000 |
|
IHC positive control: |
Human colon cancer and Human ovarian cancer |
|
IHC Recommend dilution: |
25-100 |
|
WB Predicted band size: |
53 kDa |
|
WB Positive control: |
231 cells |
|
WB Recommended dilution: |
500-2000 |
