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Background: |
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. |
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Applications: |
IHC, IF |
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Name of antibody: |
ELK1(Phospho-Thr417) |
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Immunogen: |
Peptide sequence around phosphorylation site of threonine 417(L-S-T(p)-P-V) derived from Human Elk1. |
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Full name: |
ELK1, member of ETS oncogene family |
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Synonyms: |
0 |
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SwissProt: |
P19419 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
100-200 |

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