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    • 品牌 : 通蔚生物
    • 目錄號 : TW19421
    • 應(yīng)用 : 僅供科研使用
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    • 規(guī)格 :100ul/200ul/25ul
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中文名稱:  兔抗PTPRJ多克隆抗體 

英文名稱: Anti-PTPRJ rabbit polyclonal antibody

別    名: DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA

相關(guān)類別: 一抗

儲    存 冷凍(-20℃)

宿    主: Rabbit

抗    原: PTPRJ

反應(yīng)種屬: Human, Mouse

標(biāo) 記 物: Unconjugate

克隆類型:rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

PTPRJ

Immunogen:

Synthetic peptide of human PTPRJ

Full name:

Protein tyrosine phosphatase, receptor type, J

Synonyms:

DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA

SwissProt:

Q12913

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human breast cancer and Human liver cancer

IHC Recommend dilution:

25-100



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