購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗RASSF1多克隆抗體
英文名稱： Anti-RASSF1 rabbit polyclonal antibody
別 名： 123F2; RDA32; NORE2A; RASSF1A; REH3P21
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： RASSF1
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型：rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
RASSF1 |
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Immunogen: |
Fusion protein of human RASSF1 |
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Full name: |
Ras association (RalGDS/AF-6) domain family member 1 |
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Synonyms： |
123F2; RDA32; NORE2A; RASSF1A; REH3P21 |
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SwissProt: |
Q9NS23 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
20-100 |
