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Background: |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FASTK |
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Immunogen: |
Fusion protein of human FASTK |
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Full name: |
fas-activated serine/threonine kinase |
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Synonyms: |
FAST |
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SwissProt: |
Q14296 |
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IHC positive control: |
Human gastric cancer and human brain |
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IHC Recommend dilution: |
50-200 |

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