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  • 兔抗ANLN多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW2042
    • 應(yīng)用 : 僅用于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:35
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中文名稱(chēng):兔抗ANLN多克隆抗體

英文名稱(chēng): Anti-ANLN rabbit polyclonal antibody

別      名: scra; Scraps

相關(guān)類(lèi)別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

抗      原: ANLN

宿      主: Rabbit

反應(yīng)種屬: Human, Mouse

標(biāo) 記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis.

Applications:

ELISA, IHC

Name of antibody:

ANLN

Immunogen:

Fusion protein of human ANLN

Full name:

anillin, actin binding protein

Synonyms:

scra; Scraps

SwissProt:

Q9NQW6

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100