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  • 兔抗NOTCH3多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW20919
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:80
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中文名稱:  兔抗NOTCH3多克隆抗體


英文名稱:  Anti-NOTCH3 rabbit polyclonal antibody


別       名:  CASIL, CADASIL


相關(guān)類別: 一抗


儲      存:  冷凍(-20℃)


宿      主:  Rabbit


抗      原:  NOTCH3


反應(yīng)種屬:  Human, Mouse, Rat


標(biāo)  記  物:  Unconjugate


克隆類型:  rabbit polyclonal


技術(shù)規(guī)格

Background:

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Applications:

ELISA, WB, IHC

Name of antibody:

NOTCH3

Immunogen:

Synthetic peptide of human NOTCH3

Full name:

Notch 3

Synonyms:

CASIL, CADASIL

SwissProt:

Q9UM47

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

244 kDa

WB Positive control:

Human colon cancer tissue

WB Recommended dilution:

200-1000