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Background: |
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GPA33 |
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Immunogen: |
Fusion protein of human GPA33 |
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Full name: |
glycoprotein A33 (transmembrane) |
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Synonyms: |
A33 |
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SwissProt: |
Q99795 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer and human gastric cancer |
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IHC Recommend dilution: |
50-200 |

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