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Background: |
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GPBP1 |
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Immunogen: |
Fusion protein of human GPBP1 |
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Full name: |
GC-rich promoter binding protein 1 |
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Synonyms: |
GPBP; SSH6; VASCULIN |
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SwissProt: |
Q86WP2 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
50-200 |

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