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  • 兔抗PLEKHG6多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW21741
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:80
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中文名稱: 兔抗PLEKHG6多克隆抗體


英文名稱: Anti-PLEKHG6 rabbit polyclonal antibody


別      名: MyoGEF


相關類別: 一抗


儲     存: 冷凍(-20℃)


宿     主: Rabbit


抗      原: PLEKHG6


反應種屬: Human, Mouse


標  記  物: Unconjugate


克隆類型: rabbit polyclonal


技術規(guī)格

Background:

PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

Applications:

ELISA, WB, IHC

Name of antibody:

PLEKHG6

Immunogen:

Fusion protein of human PLEKHG6

Full name:

pleckstrin homology domain containing, family G (with RhoGef domain) member 6

Synonyms:

MyoGEF

SwissProt:

Q3KR16

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer and human cervical cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

89 kDa

WB Positive control:

231 cells

WB Recommended dilution:

500-2000