購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗PLEKHG6多克隆抗體
英文名稱(chēng)： Anti-PLEKHG6 rabbit polyclonal antibody
別 名： MyoGEF
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PLEKHG6
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
PLEKHG6 |
|
Immunogen: |
Fusion protein of human PLEKHG6 |
|
Full name: |
pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
|
Synonyms： |
MyoGEF |
|
SwissProt: |
Q3KR16 |
|
ELISA Recommended dilution: |
2000-5000 |
|
IHC positive control: |
Human lung cancer and human cervical cancer |
|
IHC Recommend dilution: |
100-300 |
|
WB Predicted band size: |
89 kDa |
|
WB Positive control: |
231 cells |
|
WB Recommended dilution: |
500-2000 |
