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  • 兔抗PPP2R2B多克隆抗體

    規(guī)格：
    價格：￥
    • 品牌 : 通蔚生物
    • 目錄號 : TW21892
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：80
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中文名稱：   兔抗PPP2R2B多克隆抗體


英文名稱：   Anti-PPP2R2B rabbit polyclonal antibody


別       名：   PR52B; SCA12; B55BETA; PR55BETA; PP2ABBETA; PP2APR55B; PR2ABBETA; PR55-BETA; PP2AB55BETA; PR2AB55BETA;PP2APR55BETA; PR2APR55BETA


相關(guān)類別：   一抗

 

儲      存：   冷凍（-20℃） 避光


宿       主：   Rabbit


抗      原：  PPP2R2B


反應(yīng)種屬：  Human Mouse Rat


標(biāo)  記  物：  Unconjugate


克隆類型：  rabbit polyclonal


技術(shù)規(guī)格

Background:

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12.

Applications:

WB

Name of antibody:

PPP2R2B

Immunogen:

Synthesized peptide derived from internal of human PPP2R2B.

Full name:

protein phosphatase 2, regulatory subunit B, beta

Synonyms：

PR52B; SCA12; B55BETA; PR55BETA; PP2ABBETA; PP2APR55B; PR2ABBETA; PR55-BETA; PP2AB55BETA; PR2AB55BETA; PP2APR55BETA; PR2APR55BETA

SwissProt:

Q00005

WB Predicted band size:

56 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000