購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. |
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Applications: |
WB |
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Name of antibody: |
SNCA(Ab-125) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human Synuclein-α around the phosphorylation site of tyrosine 125 (E-A-Y(p)-E-M). |
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Full name: |
synuclein, alpha (non A4 component of amyloid precursor) |
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Synonyms： |
PD1; NACP; PARK1; PARK4 |
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SwissProt: |
P37840 |
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WB Predicted band size: |
14 kDa |
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WB Positive control: |
Rat brain and mouse brain tissue lysates |
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WB Recommended dilution: |
500-3000 |
