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Background: |
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
SPR |
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Immunogen: |
Synthetic peptide of human SPR |
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Full name: |
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
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Synonyms: |
SDR38C1 |
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SwissProt: |
P35270 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human breast cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
28 kDa |
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WB Positive control: |
Human chromaffin cells tumor tissue and lovo cells |
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WB Recommended dilution: |
500-2000 |

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