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Background: |
proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
SRC (Phospho-Tyr529) |
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Immunogen: |
Synthetic peptide of human SRC (Phospho-Tyr529) |
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Full name: |
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (Phospho-Tyr529) |
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Synonyms: |
ASV; SRC1; c-SRC; p60-Src |
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SwissProt: |
P12931 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
60 kDa |
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WB Positive control: |
HT29 cells untreated or treated with PMA |
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WB Recommended dilution: |
500-1000 |
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IF Positive control: |
Hela cells |
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IF Recommended dilution |
100-200 |


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