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Background: |
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
SUFU |
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Immunogen: |
Fusion protein of human SUFU |
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Full name: |
SUFU negative regulator of hedgehog signaling |
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Synonyms: |
SUFUH; JBTS32; SUFUXL; PRO1280 |
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SwissProt: |
Q9UMX1 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer and Human colon cancer |
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IHC Recommend dilution: |
15-50 |
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WB Predicted band size: |
54 kDa |
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WB Positive control: |
Jurkat cells |
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WB Recommended dilution: |
200-1000 |

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